Research progress on the correlation between multimodal MRI brain imaging and inflammatory markers in depression

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LING Yanxin WANG Yuting DENG Jie YANG Hongli CHENG Yan QIU Lihua

Cite this article as: LING Y X, WANG Y T, DENG J, et al. Research progress on the correlation between multimodal MRI brain imaging and inflammatory markers in depression[J]. Chin J Magn Reson Imaging, 2025, 16(4): 126-131, 144. DOI:10.12015/issn.1674-8034.2025.04.020.

Abstract

[Abstract] The incidence rate of depression and suicide rate have been rising year by year, and this has become a serious global public health issue. In recent years, some studies have shown that peripheral blood inflammatory markers are closely related to the pathophysiological processes of depression. The correlation between inflammatory markers and depression can be characterized by multimodal MRI, which further deepens the exploration into the progression of depression, the selection of treatment targets, and prognosis assessment. This review briefly summarizes recent research on the correlation between inflammatory markers and the imaging characteristics of multimodal MRI in depression, as well as potential limitations, aiming to provide direction for future studies.

[Keywords] depression；inflammation；multimodal magnetic resonance imaging；magnetic resonance imaging

Contributor Information

LING Yanxin^{1,
2}   WANG Yuting²   DENG Jie³   YANG Hongli^{1,
2}   CHENG Yan^{1,
2}   QIU Lihua^{1,
2,
4*}

¹ Department of Radiology, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China

² Medical Imaging Center of Yibin Second People's Hospital, Yibin 644000, China

³ Radiology Department of Yibin Fourth People's Hospital, Yibin 644000, China

⁴ Yibin Second People's Hospital·Clinical Medicine Research and Transformation Center of West China Hospital, Sichuan University, Big Data Research Center for Neuroimaging, Yibin 644000, China

Corresponding author: QIU L H, E-mail: qlh20050616@foxmail.com

Conflicts of interest None.

Publication Information

Received 2025-02-08

Accepted 2025-04-10

DOI: 10.12015/issn.1674-8034.2025.04.020

Text

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