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Advances in the application of magnetic resonance imaging in the localization of therapeutic targets for transcranial magnetic stimulation in depression

Cite this article as: LUO X, ZHANG B. Advances in the application of magnetic resonance imaging in the localization of therapeutic targets for transcranial magnetic stimulation in depression[J]. Chin J Magn Reson Imaging, 2023, 14(11): 150-154. DOI:10.12015/issn.1674-8034.2023.11.025.

[Abstract] Transcranial magnetic stimulation (TMS) is widely used in clinical interventions for depression, but its efficacy varies, possibly due to differences in target site localization. In recent years, with the development of magnetic resonance imaging (MRI) technology, the use of MRI structural and functional data to identify TMS targets for antidepressant effects has become a research hotspot. Therefore, this review summarized the application progress of MRI in TMS target site selection for depression treatment, including the following aspects: Precise brain region delineation and definition of millimeter-level target coordinates using MRI structural imaging; Determination of individualized stimulation target locations by calculating functional connectivity and effective connectivity parameters from MRI functional imaging; The use of MRI structural imaging for assisted targeting to help operators accurately locate the target stimulation sites. This review aims to compile relevant research and provide references for improving the clinical efficacy of TMS.
[Keywords] magnetic resonance imaging;transcranial magnetic stimulation;functional connectivity;task-based functional magnetic resonance imaging;depression

LUO Xin1   ZHANG Bin2*  

1 Psychological and Psychiatric Neuroimage Lab, Affiliated Brain Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province, the Ministry of Education of China, Guangzhou Medical University, Guangzhou 510370, China

2 Psychological and Psychiatric Lab, Tianjin Anding Hospital, Tianjin 300074, China

Corresponding author: ZHANG B, E-mail:

Conflicts of interest   None.

ACKNOWLEDGMENTS Guangdong Science and Technology Project (No. 2019B030316001).
Received  2023-05-06
Accepted  2023-10-13
DOI: 10.12015/issn.1674-8034.2023.11.025
Cite this article as: LUO X, ZHANG B. Advances in the application of magnetic resonance imaging in the localization of therapeutic targets for transcranial magnetic stimulation in depression[J]. Chin J Magn Reson Imaging, 2023, 14(11): 150-154. DOI:10.12015/issn.1674-8034.2023.11.025.

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