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Clinical Article
A Meta-analysis of myocardial tissue characteristics in patients with pulmonary hypertention evaluated by MR T1 mapping
YAN Chunlong  JIA Siqi  JIN Yuhua  QI Xianlong  SUN Yanqiu 

Cite this article as: YAN C L, JIA S Q, JIN Y H, et al. A Meta-analysis of myocardial tissue characteristics in patients with pulmonary hypertention evaluated by MR T1 mapping[J]. Chin J Magn Reson Imaging, 2023, 14(11): 38-41, 96. DOI:10.12015/issn.1674-8034.2023.11.007.

[Abstract] Objective To evaluate the diagnostic value of quantitative T1 mapping in cardiac magnetic resonance imaging for myocardial tissue characteristics in patients with pulmonary hypertention (PH) by Meta-analysis.Materials and Methods Relevant literatures were retrieved from Pubmed, Web of Science, the Cochrane Library, CNKI, Wanfang Database and VIP Database from the establishment of the database to December 31, 2022. Two researchers independently screened literatures, extracted data and evaluated the quality of the included literatures according to the inclusion and exclusion criteria. Meta-analysis was performed using Revman 5.4 software.Results A total of 8 literatures were included, including 613 PH patients and 150 healthy controls. The results of Meta-analysis showed that compared with the healthy control group, the initial T1 value of PH patients was significantly increased [odds ratio (OR)=123.22, 95% CI (112.92-133.52), P<0.001]. Myocardial damage was obvious in inferior right ventricle insertion point (IRVIP) in PH group [OR=-82.94, 95% CI (-92.43--73.45), P<0.001].Conclusions MR T1 mapping technique can evaluate the myocardial tissue characteristics of PH patients noninvasculatively, which has high clinical application value. Close attention should be paid to the myocardium of IRVIP.
[Keywords] cardiac magnetic resonance;T1 mapping;pulmonary hypertention;Meta-analysis;magnetic resonance imaging

YAN Chunlong1, 2, 3   JIA Siqi4   JIN Yuhua4   QI Xianlong1*   SUN Yanqiu3*  

1 Department of Radiology, Jining No.1 People's Hospital, Jining 272000, China

2 Graduate School, Soochow University, Suzhou 215004, China

3 CT Room, Qinghai Provincial People's Hospital, Xining 810007, China

4 School of Clinical Medicine, Jining Medical University, Jining 272000, China

Corresponding author: QI X L, E-mail: SUN Y Q, E-mail:

Conflicts of interest   None.

ACKNOWLEDGMENTS Qinghai Provincial Health Committee Guiding Program Project (No. 2020-wjzdx-04); Qinghai Provincial Department of Science and Technology Basic Research Project (No. 2021-ZJ-732); Qinghai Province "Kunlun Elite High-end Innovative and Entrepreneurial Talents" Program to Cultivate Leading Talents (Youth Talent Word 2021 No. 13); Key R&D Program of Jining (No. 2023YXNS103).
Received  2023-01-10
Accepted  2023-10-23
DOI: 10.12015/issn.1674-8034.2023.11.007
Cite this article as: YAN C L, JIA S Q, JIN Y H, et al. A Meta-analysis of myocardial tissue characteristics in patients with pulmonary hypertention evaluated by MR T1 mapping[J]. Chin J Magn Reson Imaging, 2023, 14(11): 38-41, 96. DOI:10.12015/issn.1674-8034.2023.11.007.

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