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Progresseson MRI characteristics of the effect of cerebral small vessel disease on cognitive function in patients with type 2 diabetes mellitus
LIU Yangyingqiu  MIAO Yanwei 

Cite this article as: LIU Y Y Q, MIAO Y W. Progresseson MRI characteristics of the effect of cerebral small vessel disease on cognitive function in patients with type 2 diabetes mellitus[J]. Chin J Magn Reson Imaging, 2023, 14(10): 141-146. DOI:10.12015/issn.1674-8034.2023.10.025.

[Abstract] Cognitive impairment is a main symptom of brain damage in type 2 diabetes mellitus (T2DM) patients.The cognitive function decline of T2DM patients may be mediated by microvascular injury which caused by chronic hyperglycemia.We reviewed the anatomy, pathology and MRI features of cerebral small vascular disease (CSVD)(recent small subcortical infarct, lacune, white matter hyperintensity, perivascular space, cerebral microbleed, cortical superficial siderosis, cortical microinfarct, atrophy), the CSVD factors of cognitive decline in T2DM patients, and the progress of radiomics research of CSVD MRI features in this paper, in order to provide ideas for further research and clinical diagnosis and treatment.
[Keywords] type 2 diabetes mellitus;cerebral small vessel disease;cognitive impairment;white matter hyperintensity;radiomics;diffusion tensor imaging;susceptibility weighted imaging;magnetic resonance imaging

LIU Yangyingqiu1, 2   MIAO Yanwei1*  

1 Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian 116000, China

2 Department of Radiology, Zibo Central Hospital, Zibo 255000, China

Corresponding author: MIAO Y W, E-mail:

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 81671646).
Received  2023-05-09
Accepted  2023-09-14
DOI: 10.12015/issn.1674-8034.2023.10.025
Cite this article as: LIU Y Y Q, MIAO Y W. Progresseson MRI characteristics of the effect of cerebral small vessel disease on cognitive function in patients with type 2 diabetes mellitus[J]. Chin J Magn Reson Imaging, 2023, 14(10): 141-146. DOI:10.12015/issn.1674-8034.2023.10.025.

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