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Research progress of quantitative MRI technique in temporal lobe epilepsy
XU Donghao  LIU Miaomiao  LIU Yuwei  GONG He  LI Xianglin 

Cite this article as: XU D H, LIU M M, LIU Y W, et al. Research progress of quantitative MRI technique in temporal lobe epilepsy[J]. Chin J Magn Reson Imaging, 2023, 14(7): 144-148, 170. DOI:10.12015/issn.1674-8034.2023.07.026.

[Abstract] Temporal lobe epilepsy (TLE) is a type of epilepsy based on the abnormal discharge of neurons in the temporal lobe region. The incidence of TLE in patients with epilepsy is about 40%. medial temporal sclerosis (MTS) is the most common cause of drug-resistant focal epilepsy. Surgical treatment is the first choice for the treatment. Conventional structural MRI, as an important preoperative reference for patients with refractory TLE, cannot accurately localize and lateralize the epileptogenic zone. Quantitative MRI technology can provide more objective and accurate structural and functional information through quantitative or semi-quantitative methods, and has higher sensitivity than structural MRI. This article will briefly introduce the quantitative imaging technology related to TLE, including relaxation time, metabolic level, tissue microstructure and perfusion imaging, and review its application progress in the diagnosis and treatment of TLE and TLE network research, aiming to assist in the accurate localization of epileptogenic zone, the evaluation of lesion degree, and the formulation of individualized treatment plan during the diagnosis and treatment of TLE.
[Keywords] temporal lobe epilepsy;medial temporal sclerosis;magnetic resonance imaging;quantitative magnetic resonance imaging;biomarker

XU Donghao   LIU Miaomiao   LIU Yuwei   GONG He   LI Xianglin*  

School of Medical Imaging, Binzhou Medical University, Yantai 264003, China

Corresponding author: Li XL, E-mail:

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 62176181); Key R & D Plan of Shandong Province (No. 2018YFJH0501).
Received  2023-01-13
Accepted  2023-06-25
DOI: 10.12015/issn.1674-8034.2023.07.026
Cite this article as: XU D H, LIU M M, LIU Y W, et al. Research progress of quantitative MRI technique in temporal lobe epilepsy[J]. Chin J Magn Reson Imaging, 2023, 14(7): 144-148, 170. DOI:10.12015/issn.1674-8034.2023.07.026.

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