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Research progress of MRI on pathological changes and cognitive impairment of radiation-induced brain injury
ZHANG Danni  ZOU Qiaoqiao  WANG Mingliang  LI Wenbin 

Cite this article as: ZHANG D N, ZOU Q Q, WANG M L, et al. Research progress of MRI on pathological changes and cognitive impairment of radiation-induced brain injury[J]. Chin J Magn Reson Imaging, 2023, 14(5): 155-160. DOI:10.12015/issn.1674-8034.2023.05.027.

[Abstract] Cognitive function impairment is the most common clinical manifestation of radiation-induced brain injury. The diagnosis is mainly based on clinical features and neuropsychological scales. The process of cognitive function impairment after radiotherapy is related to the pathological changes. This article reviews the latest progress in the pathological processes related to cognitive function impairment after radiotherapy and the application of MRI. It summarizes the early imaging manifestations and corresponding pathological changes of radiation-induced brain injury in different sequences, and the application of artificial intelligence and radiomics based on MRI in predicting patients with cognitive function impairment after radiotherapy. Based on this, the research direction of artificial intelligence and radiomics combined with multi-sequence MRI for early diagnosis of cognitive function impairment after radiotherapy is proposed, which is helpful for early and accurate identification of patients with cognitive function impairment after radiotherapy and early intervention to improve the quality of life of patients.
[Keywords] radiation-induced brain injury;pathological changes;cognitive impairment;magnetic resonance imaging

ZHANG Danni   ZOU Qiaoqiao   WANG Mingliang   LI Wenbin*  

Department of Radiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China

Corresponding author: Li WB, E-mail:

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 81901727).
Received  2022-11-29
Accepted  2023-05-06
DOI: 10.12015/issn.1674-8034.2023.05.027
Cite this article as: ZHANG D N, ZOU Q Q, WANG M L, et al. Research progress of MRI on pathological changes and cognitive impairment of radiation-induced brain injury[J]. Chin J Magn Reson Imaging, 2023, 14(5): 155-160. DOI:10.12015/issn.1674-8034.2023.05.027.

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