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Research progress of brain structural and functional magnetic resonance imaging in patients with chronic pruritus disease
LU Zhikai  NIU Jinliang 

Cite this article as: LU Z K, NIU J L. Research progress of brain structural and functional magnetic resonance imaging in patients with chronic pruritus disease[J]. Chin J Magn Reson Imaging, 2023, 14(5): 150-154. DOI:10.12015/issn.1674-8034.2023.05.026.

[Abstract] Chronic pruritus (CP) refers to itching lasting for 6 weeks or more, which is the most common clinical symptom of various skin diseases and systemic diseases, seriously affecting the patient's sleep, social interaction and work, and reducing the quality of life. Great progress has been made in the research of CP at the peripheral and spinal cord levels, and the central pathophysiological mechanism related to pruritus is the focus of current research. Voxel-based morphometry, diffusion tensor imaging, and functional magnetic resonance imaging are the main methods for quantitative analysis of brain structure and function. This paper mainly reviewed the research status of brain microstructure, abnormal activated regions and brain network changes related to central imaging studies of CP. It provides imaging evidence for guiding diagnosis, monitoring efficacy, targeted drug development and non-drug intervention.
[Keywords] chronic pruritus;brain structure;brain function;functional magnetic resonance imaging;voxel-based morphometry analysis;diffusion tensor imaging

LU Zhikai1   NIU Jinliang2*  

1 CT Room, General Hospital of Taiyuan Iron and Steel (Group) Co., Ltd. (the Sixth Hospital of Shanxi Medical University), Taiyuan 030008, China

2 Department of Imaging, the Second Hospital of Shanxi Medical University, Taiyuan 030001, China

Corresponding author: Niu JL, E-mail:

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82071898); Research Project of Health Commission of Shanxi Province (No. 2020-1).
Received  2022-11-19
Accepted  2023-04-28
DOI: 10.12015/issn.1674-8034.2023.05.026
Cite this article as: LU Z K, NIU J L. Research progress of brain structural and functional magnetic resonance imaging in patients with chronic pruritus disease[J]. Chin J Magn Reson Imaging, 2023, 14(5): 150-154. DOI:10.12015/issn.1674-8034.2023.05.026.

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