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Application of deep learning in intravoxel incoherent motion brain magnetic resonance imaging quality
LI Qiongge  Yayan YIN  ZHAO Cheng  QI Zhigang  LU Jie 


[Abstract] Objective To explore the clinical implication of deep learning (DL) reconstruction in accelerate intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI).Materials and Methods Based on 3.0 T MRI system, a total of 40 healthy subjects were collected for accelerated IVIM data acquisition (DL_IVIM) based on DL reconstruction with excitation times (i.e. signal acquisition times) of 1 and conventional image acquisition (ORIG_IVIM) with excitation times of 2. Wilcoxon rank-sum test was used to compare scan time, signal of noise ratio (SNR), non-uniformity index (NUI), quantitative parameters [diffusion coefficient (D value), pseudo-diffusion coefficient (D* value) and perfusion fraction (F value)]. The χ2 test was used to compare the subjective ratings of DL_IVIM and ORGI_IVIM.Results Compared with ORIG_IVIM, the scan time of DL_IVIM was reduced by 23.4%. In addition, SNR (except b=0 s/mm2) and subjective scores of DL_IVIM were significantly higher than those of ORIG_IVIM (P<0.05), NUI (except b=0 s/mm2) were significantly lower than those of ORIG_IVIM (P<0.05), there was no significant difference in D, D* and F values (P>0.05). DL_IVIM score was significantly higher than ORIG_IVIM (χ2=32.81, P<0.001).Conclusions DL reconstruction can significantly improve the image quality of IVIM, ensure the accuracy of quantitative parameters, and shorten the scanning time, which provides valuable reference information for the application of DL reconstruction in clinical IVIM imaging.
[Keywords] intravoxel incoherent motion;deep learning;brain;diffusion weighted imaging;magnetic resonance imaging

LI Qiongge1, 2   Yayan YIN1, 2   ZHAO Cheng1, 2   QI Zhigang1, 2   LU Jie1, 2*  

1 Department of Radiology and Nuclear Medicine, Xuanwu Hospital Capital Medical University, Beijing 100053, China

2 Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing 100053, China

Corresponding author: Lu J, E-mail:

Conflicts of interest   None.

Received  2023-01-04
Accepted  2023-04-11
DOI: 10.12015/issn.1674-8034.2023.05.004

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