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The value of modified MRI-DRAGON score in predicting the outcome of acute ischemic stroke after endovascular treatment
WANG Xiuling  WANG Xuan  WANG Mengdi  WANG Tongxing  YIN Xindao  PENG Mingyang 

Cite this article as: WANG X L, WANG X, WANG M D, et al. The value of modified MRI-DRAGON score in predicting the outcome of acute ischemic stroke after endovascular treatment[J]. Chin J Magn Reson Imaging, 2023, 14(3): 134-139. DOI:10.12015/issn.1674-8034.2023.03.023.

[Abstract] Objective To investigate the predictive value of modified MRI-DRAGON score in the outcome of acute ischemic stroke after endovascular treatment.Materials and Methods Cases of patients with acute ischemic stroke underwent endovascular treatment in the two hospitals from January 2020 to December 2021 were enrolled retrospectively. Modified MRI-DRAGON and MRI-DRAGON score were evaluated and compared according to the clinical and MRI variables. The outcome at 3 month was evaluated with the modified Rankin Scale (mRS) at 3 months after treatment (0-2 points for good outcome and 3-6 points for poor outcome). Logistic regression analysis was used to calculate the C-statistic value of MRI-DRAGON score and modified MRI-DRAGON score in predicting poor outcome of stroke. The receiver operating characteristic (ROC) curve was used to analyze the predictive value of two methods for outcome, and the difference was compared by DeLong test.Results A total of 95 patients were included, including 49 patients with good outcome and 46 patients with poor outcome. There was significant difference between the MRI-DRAGON score (Z=5.046, P=0.023) and modified MRI-DRAGON score (Z=-4.429, P<0.001) between two groups. Logistic regression analysis showed that the modified MRI-DRAGON score was significantly higher than MRI-DRAGON score [0.87 (95% CI: 0.78-0.90) vs. 0.77 (95% CI: 0.65-0.81)] in predicting poor outcome of stroke. ROC curve showed that the area under the curve of modified MRI-DRAGON score was significantly higher than that of MRI-DRAGON score in predicting poor outcome of stroke (0.889 vs. 0.757; Z=-2.294, P=0.022), and its sensitivity and specificity reached 91.3% and 87.3%, respectively.Conclusions Comparing with the traditional MRI-DRAGON score, the modified MRI-DRAGON score can more effectively predict the clinical outcome of patients with acute ischemic stroke at 3 months after endovascular treatment.
[Keywords] stroke;DRAGON score;endovascular treatment;magnetic resonance imaging;diffusion weighted imaging;magnetic resonance angiography;endovascular treatment;outcome

WANG Xiuling1   WANG Xuan1   WANG Mengdi2   WANG Tongxing3   YIN Xindao3   PENG Mingyang3*  

1 Department of Radiology, Jinhu County People's Hospital, Huaian 211699, China

2 Department of Neurology, Jinhu County People's Hospital, Huaian 211699, China

3 Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

Corresponding author: Peng MY, E-mail:

Conflicts of interest   None.

Received  2022-11-23
Accepted  2023-03-01
DOI: 10.12015/issn.1674-8034.2023.03.023
Cite this article as: WANG X L, WANG X, WANG M D, et al. The value of modified MRI-DRAGON score in predicting the outcome of acute ischemic stroke after endovascular treatment[J]. Chin J Magn Reson Imaging, 2023, 14(3): 134-139. DOI:10.12015/issn.1674-8034.2023.03.023.

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