Share:
Share this content in WeChat
X
Review
Progress of imaging studies of the patients with cardiac involvement in polymyositis/dermatomyositis
WANG Rong  LI Zhoule  WANG Yongle  WANG Haijun  XIE Ping 

Cite this article as: Wang R, Li ZL, Wang YL, et al. Progress of imaging studies of the patients with cardiac involvement in polymyositis/dermatomyositis[J]. Chin J Magn Reson Imaging, 2022, 13(11): 141-144. DOI:10.12015/issn.1674-8034.2022.11.028.


[Abstract] Polymyositis (PM) and dermatomyositis (DM) are autoimmune diseases. Cardiac involvement has become the leading cause of death in patients with PM/DM. The onset of cardiac involvement is usually hidden. Early diagnosis is helpful to start effective treatment and improve prognosis. At present, the application value of conventional imaging for subclinical cardiac involvement is limited, and functional imaging has potential value. Multimodal functional imaging plays an important role in the early diagnosis and efficacy evaluation of cardiac involvement in PM/DM. This article reviews the application and research progress of multimodal imaging in the early diagnosis and quantitative assessment of cardiac damage in patients with PM/DM.
[Keywords] polymyositis;dermatomyositis;idiopathic inflammatory myopathy;heart;early diagnosis;efficacy evaluation;magnetic resonance imaging;cardiac magnetic resonance;single photon emission tomography

WANG Rong1, 2   LI Zhoule3   WANG Yongle1   WANG Haijun1*   XIE Ping2, 4*  

1 Department of Nuclear Medicine, Gansu Provincial Hospital, Lanzhou 730000, China

2 The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China

3 First Clinical Medical College of Gansu University of Chinese Medicine, Lanzhou 730000, China

4 Department of Cardiology, Gansu Provincial Hospital, Lanzhou 730000, China

Wang HJ, E-mail: whj1425@126.com Xie P, E-mail: pingxie66@163.com

Conflicts of interest   None.

Received  2021-10-28
Accepted  2022-10-13
DOI: 10.12015/issn.1674-8034.2022.11.028
Cite this article as: Wang R, Li ZL, Wang YL, et al. Progress of imaging studies of the patients with cardiac involvement in polymyositis/dermatomyositis[J]. Chin J Magn Reson Imaging, 2022, 13(11): 141-144.DOI:10.12015/issn.1674-8034.2022.11.028

[1]
Opinc AH, Makowski MA, Łukasik ZM, et al. Cardiovascular complications in patients with idiopathic inflammatory myopathies: does heart matter in idiopathic inflammatory myopathies?[J]. Heart Fail Rev, 2021, 26(1): 111-125. DOI: 10.1007/s10741-019-09909-8.
[2]
Jia YL, Wu XQ, Zheng Y, et al. Value of short-tau inversion recovery sequences in the MR imaging diagnosis of polymyositis and dermatomyositis[J]. Chin J Magn Reson Imaging, 2018, 9(2): 139-143. DOI: 10.12015/issn.1674-8034.2018.02.012.
[3]
Yu LY, Sun JH, Sun JY, et al. Early detection of myocardial involvement by T1 mapping of cardiac MRI in idiopathic inflammatory myopathy[J]. J Magn Reson Imaging, 2018, 48(2): 415-422. DOI: 10.1002/jmri.25945.
[4]
Liu YX, Fang LG, Chen W, et al. Clinical characteristics, treatment, and outcomes in patients with idiopathic inflammatory myopathy concomitant with heart failure[J]. Int Heart J, 2020, 61(5): 1005-1013. DOI: 10.1536/ihj.19-568.
[5]
Zhou S, Lai JZ, Wu CY, et al. Myocardial involvement is not rare in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis/clinically amyopathic dermatomyositis: a retrospective study[J/OL]. Front Immunol, 2022, 13 [2022-09-12]. https://doi.org/10.3389/fimmu.2022.928861. DOI: 10.3389/fimmu.2022.928861.
[6]
Witczak BN, Schwartz T, Barth Z, et al. Associations between cardiac and pulmonary involvement in patients with juvenile dermatomyositis-a cross-sectional study[J]. RheumatolInt, 2022, 42(7): 1213-1220. DOI: 10.1007/s00296-021-05071-3.
[7]
Huang YF, Liu HZ, Wu CY, et al. Ventricular arrhythmia predicts poor outcome in polymyositis/dermatomyositis with myocardial involvement[J]. Rheumatology (Oxford), 2021, 60(8): 3809-3816. DOI: 10.1093/rheumatology/keaa872.
[8]
Liu XH, Feng XJ, Shi JY, et al. The quest for diagnostic approaches of cardiac involvement in polymyositis and dermatomyositis[J]. Ann Palliat Med, 2020, 9(4): 2256-2270. DOI: 10.21037/apm-19-650.
[9]
Schwartz T, Diederichsen LP, Lundberg IE, et al. Cardiac involvement in adult and juvenile idiopathic inflammatory myopathies[J/OL]. RMD Open, 2016, 2(2) [2022-09-12]. https://doi.org/10.1136/rmdopen-2016-000291. DOI: 10.1136/rmdopen-2016-000291.
[10]
Zhang LX, Zhu HY, Yang PT, et al. Myocardial involvement in idiopathic inflammatory myopathies: a multi-center cross-sectional study in the CRDC-MYO Registry[J]. Clin Rheumatol, 2021, 40(11): 4597-4608. DOI: 10.1007/s10067-021-05828-y.
[11]
Diederichsen LP, Diederichsen AC, Simonsen JA, et al. Traditional cardiovascular risk factors and coronary artery calcification in adults with polymyositis and dermatomyositis: a Danish multicenter study[J]. Arthritis Care Res (Hoboken), 2015, 67(6): 848-854. DOI: 10.1002/acr.22520.
[12]
de Moraes MT, de Souza FH, de Barros TB, et al. Analysis of metabolic syndrome in adult dermatomyositis with a focus on cardiovascular disease[J]. Arthritis Care Res (Hoboken), 2013, 65(5): 793-799. DOI: 10.1002/acr.21879.
[13]
Diederichsen LP. Cardiovascular involvement in myositis[J]. Curr Opin Rheumatol, 2017, 29(6): 598-603. DOI: 10.1097/BOR.0000000000000442.
[14]
Fardet L, Fève B. Systemic glucocorticoid therapy: a review of its metabolic and cardiovascular adverse events[J]. Drugs, 2014, 74(15): 1731-1745. DOI: 10.1007/s40265-014-0282-9.
[15]
Faccini A, Kaski JC, Camici PG. Coronary microvascular dysfunction in chronic inflammatory rheumatoid diseases[J]. Eur Heart J, 2016, 37(23): 1799-1806. DOI: 10.1093/eurheartj/ehw018.
[16]
Xiao YZ, Luo H, Liu SQ, et al. Is it cardiac involvement mimicking acute myocardial infarction in idiopathic inflammatory myopathy?[J]. Exp Ther Med, 2017, 14(1): 349-354. DOI: 10.3892/etm.2017.4447.
[17]
Zhang YL, Zhang Y, Wang CH, et al. Clinical features and CMR imaging findings of myocarditis induced by dermatomyositis: one case report[J]. Chin J Magn Reson Imaging, 2022, 13(8): 96-97. DOI: 10.12015/issn.1674-8034.2022.08.020.
[18]
Deveza LM, Miossi R, de Souza FH, et al. Electrocardiographic changes in dermatomyositis and polymyositis[J]. Rev Bras ReumatolEngl Ed, 2016, 56(2): 95-100. DOI: 10.1016/j.rbre.2014.08.012.
[19]
Qiu MQ, Sun XX, Qi XQ, et al. The diagnostic value of GDF-15 for myocardial involvement in idiopathic inflammatory myopathy[J]. Rheumatology (Oxford), 2021, 60(6): 2826-2833. DOI: 10.1093/rheumatology/keaa721.
[20]
Sinagra G, Porcari A, Fabris E, et al. Standardizing the role of endomyocardial biopsy in current clinical practice worldwide[J]. Eur J Heart Fail, 2021, 23(12): 1995-1998. DOI: 10.1002/ejhf.2380.
[21]
Khoo T, Stokes MB, Teo K, et al. Cardiac involvement in idiopathic inflammatory myopathies detected by cardiac magnetic resonance imaging[J]. Clin Rheumatol, 2019, 38(12): 3471-3476. DOI: 10.1007/s10067-019-04678-z.
[22]
Wang H, Tang J, Chen X, et al. Lipid profiles in untreated patients with dermatomyositis[J]. J Eur Acad Dermatol Venereol, 2013, 27(2): 175-179. DOI: 10.1111/j.1468-3083.2011.04437.x.
[23]
Péter A, Balogh Á, Csanádi Z, et al. Subclinical systolic and diastolic myocardial dysfunction in polyphasic polymyositis/dermatomyositis: a 2-year longitudinal study[J/OL]. Arthritis Res Ther, 2022, 24(1)[2022-09-12]. https://doi.org/10.1186/s13075-022-02906-7. DOI: 10.1186/s13075-022-02906-7.
[24]
Romano S, Judd RM, Kim RJ, et al. Feature-tracking global longitudinal strain predicts mortality in patients with preserved ejection fraction: a multicenter study[J]. JACC Cardiovasc Imaging, 2020, 13(4): 940-947. DOI: 10.1016/j.jcmg.2019.10.004.
[25]
Zhong Y, Bai WJ, Xie QB, et al. Cardiac function in patients with polymyositis or dermatomyositis: a three-dimensional speckle-tracking echocardiography study[J]. Int J Cardiovasc Imaging, 2018, 34(5): 683-693. DOI: 10.1007/s10554-017-1278-9.
[26]
Guerra F, Gelardi C, Capucci A, et al. Subclinical cardiac dysfunction in polymyositis and dermatomyositis: a speckle-tracking case-control study[J]. J Rheumatol, 2017, 44(6): 815-821. DOI: 10.3899/jrheum.161311.
[27]
Rosenbohm A, Buckert D, Gerischer N, et al. Early diagnosis of cardiac involvement in idiopathic inflammatory myopathy by cardiac magnetic resonance tomography[J]. J Neurol, 2015, 262(4): 949-956. DOI: 10.1007/s00415-014-7623-1.
[28]
Mavrogeni S, Douskou M, Manoussakis MN. Contrast-enhanced CMR imaging reveals myocardial involvement in idiopathic inflammatory myopathy without cardiac manifestations[J]. JACC Cardiovasc Imaging, 2011, 4(12): 1324-1325. DOI: 10.1016/j.jcmg.2011.05.009.
[29]
Friedrich MG, Sechtem U, Schulz-Menger J, et al. Cardiovascular magnetic resonance in myocarditis: a JACC White Paper[J]. J Am Coll Cardiol, 2009, 53(17): 1475-1487. DOI: 10.1016/j.jacc.2009.02.007.
[30]
Sun JH, Yin G, Xu YW, et al. Phenotyping of myocardial involvement by cardiac magnetic resonance in idiopathic inflammatory myopathies[J]. Eur Radiol, 2021, 31(7): 5077-5086. DOI: 10.1007/s00330-020-07448-7.
[31]
Messroghli DR, Moon JC, Ferreira VM, et al. Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: a consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI)[J/OL]. J Cardiovasc Magn Reson, 2017, 19(1) [2022-09-12]. https://doi.org/10.1186/s12968-017-0389-8. DOI: 10.1186/s12968-017-0389-8.
[32]
Puntmann VO, Isted A, Hinojar R, et al. T1 and T2 mapping in recognition of early cardiac involvement in systemic sarcoidosis[J]. Radiology, 2017, 285(1): 63-72. DOI: 10.1148/radiol.2017162732.
[33]
Zhao PJ, Huang L, Ran LP, et al. CMR T1 mapping and strain analysis in idiopathic inflammatory myopathy: evaluation in patients with negative late gadolinium enhancement and preserved ejection fraction[J]. Eur Radiol, 2021, 31(3): 1206-1215. DOI: 10.1007/s00330-020-07211-y.
[34]
Feng CJ, Liu WY, Sun XX, et al. Myocardial involvement characteristics by cardiac MR imaging in patients with polymyositis and dermatomyositis[J]. Rheumatology (Oxford), 2022, 61(2): 572-580. DOI: 10.1093/rheumatology/keab271.
[35]
Huber AT, Bravetti M, Lamy J, et al. Non-invasive differentiation of idiopathic inflammatory myopathy with cardiac involvement from acute viral myocarditis using cardiovascular magnetic resonance imaging T1 and T2 mapping[J/OL]. J Cardiovasc Magn Reson, 2018, 20(1) [2022-09-12]. https://doi.org/10.1186/s12968-018-0430-6. DOI: 10.1186/s12968-018-0430-6.
[36]
Liu X, Yang ZG, Li Y. Clinical application and current research status of cardiac magnetic resonance imaging of myocardial infarction[J]. Chin J Magn Reson Imaging, 2021, 12(8): 98-100, 107. DOI: 10.12015/issn.1674-8034.2021.08.022.
[37]
Kersten J, Güleroglu AM, Rosenbohm A, et al. Myocardial involvement and deformation abnormalities in idiopathic inflammatory myopathy assessed by CMR feature tracking[J]. Int J Cardiovasc Imaging, 2021, 37(2): 597-603. DOI: 10.1007/s10554-020-02020-2.
[38]
Deng Q, Yu LY, Xu YW, et al. Layer-specific strain characteristic and diagnostic value for detecting subclinical cardiac dysfunction in polymyositis and dermatomyositis: a cardiac magnetic resonance imaging study[J]. Chin J Med Imaging, 2022, 30(7): 648-654. DOI: 10.3969/j.issn.1005-5185.2022.07.002.
[39]
Wang Y, Wang Q, Cao J, et al. Cardiovascular magnetic resonance mapping and strain assessment for the diagnosis of cardiac involvement in idiopathic inflammatory myopathy patients with preserved left ventricular ejection fraction[J]. J Thorac Imaging, 2021, 36(4): 254-261. DOI: 10.1097/RTI.0000000000000578.
[40]
He J, Yang WJ, Wu WC, et al. Early diastolic longitudinal strain rate at MRI and outcomes in heart failure with preserved ejection fraction[J]. Radiology, 2021, 301(3):582-592. DOI: 10.1148/radiol.2021210188.
[41]
Allanore Y, Vignaux O, Arnaud L, et al. Effects of corticosteroids and immunosuppressors on idiopathic inflammatory myopathy related myocarditis evaluated by magnetic resonance imaging[J]. Ann Rheum Dis, 2006, 65(2): 249-252. DOI: 10.1136/ard.2005.038679.
[42]
Xu YW, Sun JH, Wan K, et al. Multiparametric cardiovascular magnetic resonance characteristics and dynamic changes in myocardial and skeletal muscles in idiopathic inflammatory cardiomyopathy[J/OL].J Cardiovasc Magn Reson, 2020, 22(1)[2022-09-12]. https://doi.org/10.1186/s12968-020-00616-0. DOI: 10.1186/s12968-020-00616-0.
[43]
Li Y, Zhou YS, Wang Q. Multiple values of 18F-FDG PET/CT in idiopathic inflammatory myopathy[J]. Clin Rheumatol, 2017, 36(10): 2297-2305. DOI: 10.1007/s10067-017-3794-3.
[44]
Yildiz H, D'Abadie P, Gheysens O. The role of quantitative and semi-quantitative[18F]FDG-PET/CT indices for evaluating disease activity and management of patients with dermatomyositis and polymyositis[J/OL]. Front Med (Lausanne), 2022, 9 [2022-09-12]. https://doi.org/10.3389/fmed.2022.883727. DOI: 10.3389/fmed.2022.883727.
[45]
Al-Mehisen R, Alnemri K, Al-Mohaissen M. Cardiac imaging of a patient with unusual presentation of granulomatosis with polyangiitis: a case report and review of the literature[J]. J NuclCardiol, 2021, 28(2): 441-455. DOI: 10.1007/s12350-019-01809-6.
[46]
Li JM, Yang MF, He ZX. Application value of radionuclide myocardial blood flow quantitative imaging in evaluating coronary microvascular dysfunction[J]. Chin J Cardiol, 2020, 48(12): 1073-1077. DOI: 10.3760/cma.j.cn112148-20200426-00349.
[47]
Wang R, Wang Y, Wang H. Cardiac involvement in polymyositis: role of myocardial perfusion imaging[J/OL]. J NuclCardiol, 2021 [2022-09-12]. https://doi.org/10.1007/s12350-021-02744-1. DOI: 10.1007/s12350-021-02744-1.
[48]
Xu J, Feng HM, Zhang YF, et al. Polymyositis induced dilated cardiomyopathy: a misdiagnosis case report[J]. South China J Cardiovasc Dis, 2021, 27(1): 110-112. DOI: 10.3969/j.issn.1007-9688.2021.01.24.
[49]
Buchpiguel CA, Roizemblatt S, Pastor EH, et al. Cardiac and skeletal muscle scintigraphy in dermato- and polymyositis: clinical implications[J]. Eur J Nucl Med, 1996, 23(2): 199-203. DOI: 10.1007/BF01731845.
[50]
Okada Y, Takakuwa Y, Ooka S, et al. Usefulness of 123I-BMIPP and 201TlCl nuclide scintigraphy in evaluation of myocarditis in patients with polymyositis or dermatomyositis[J/OL]. Medicine, 2021, 100(36)[2022-09-12]. https://doi.org/10.1097/MD.0000000000027173. DOI: 10.1097/MD.0000000000027173.

PREV Research progress of MRI on brain plasticity in cervical spondylotic myelopathy
NEXT Myocardial fibrosis CMR and its application progress in diabetic cardiomyopathy
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn