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New progress in the application of diffusion tensor imaging in autism spectrum disorders
LI Yuxin  DANG Weili  ZHOU Rongyi  KONG Yamin  MA Bingxiang 

Cite this article as: Li YX, Dang WL, Zhou RY, et al. New progress in the application of diffusion tensor imaging in autism spectrum disorders[J]. Chin J Magn Reson Imaging, 2022, 13(11): 119-124. DOI:10.12015/issn.1674-8034.2022.11.023.

[Abstract] Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder that starts in early childhood, with a high disability rate. Therefore, timely diagnosis and early treatment are essential. The heterogeneity of ASD diagnostic methods and the inherent subjectivity of the scale evaluation are obstacles to the early recognition of ASD. Diffusion tensor imaging (DTI) can quantitatively present the changes of white matter microstructure and brain development through relevant parameters, which is of great value in early recognition and diagnosis of ASD. Therefore, based on the DTI technology and its clinical application in ASD diagnosis and treatment, this paper summarized and proposed that the future research direction of DTI technology is to explore the white matter fiber bundle connection mechanism of ASD, summarize the common development paths of different neurodevelopmental disorders, and analyze the longitudinal correlation between brain development and behavior of all age groups of children with ASD, in order to clarify the potential neuropathological mechanism and provide important reference for the future use of visualization technology to seek ASD biomarkers.
[Keywords] autism spectrum disorder;white matter fiber bundle;fractional anisotropy;biomarkers;magnetic resonance imaging;diffusion tensor imaging

LI Yuxin1, 3   DANG Weili2, 3   ZHOU Rongyi2, 3   KONG Yamin2, 3   MA Bingxiang2, 3*  

1 Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China

2 Children's Brain Disease Diagnosis, Treatment and Rehabilitation Center of the First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China

3 School of Pediatric Medicine, Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China

Ma BX, E-mail:

Conflicts of interest   None.

Received  2022-04-09
Accepted  2022-11-07
DOI: 10.12015/issn.1674-8034.2022.11.023
Cite this article as: Li YX, Dang WL, Zhou RY, et al. New progress in the application of diffusion tensor imaging in autism spectrum disorders[J]. Chin J Magn Reson Imaging, 2022, 13(11): 119-124.DOI:10.12015/issn.1674-8034.2022.11.023

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