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Application value of multi-modal imaging technique in early diagnosis of Alzheimer's disease
LI Qing  YUE Xipeng  BAI Yan  LUO Yu  WANG Meiyun 

Cite this article as: Li Q, Yue XP, Bai Y, et al. Application value of multi-modal imaging technique in early diagnosis of Alzheimer's disease[J]. Chin J Magn Reson Imaging, 2022, 13(11): 110-114. DOI:10.12015/issn.1674-8034.2022.11.021.

[Abstract] Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive cognitive impairment and memory impairment, and it is also a great challenge in the process of population aging in China. Intervention in the early stage of AD is of great significance to delay the progress of the disease and improve the prognosis. Therefore, the early diagnosis of AD is very important. Multimodal imaging technology provides important imaging evidence for the pathogenesis and early clinical diagnosis of AD from the aspects of structure, function, metabolism and so on. We reviewed multimodal imaging technology, including MRI and positron emission computed tomography (PET) technology such as structure and function, and analyzed the application value of reflecting different brain characteristics in early diagnosis of AD patients in this article, in order to reveal the early pathological changes of AD from the perspective of imaging, improve the efficiency of early diagnosis of AD, and guide clinical treatment in the future.
[Keywords] Alzheimer's disease;mild cognitive impairment;multimodal imaging technology;early diagnosis;magnetic resonance imaging;functional magnetic resonance imaging;positron emission computed tomography

LI Qing1, 2   YUE Xipeng2, 3   BAI Yan2   LUO Yu2, 3   WANG Meiyun2, 3*  

1 Xinxiang Medical University, Xinxiang 453003, China

2 Department of Medical Imaging, Henan Provincial People's Hospital, Zhengzhou 450003, China

3 Department of Medical Imaging, Zhengzhou University People's Hospital, Zhengzhou 450003, China

Wang MY, E-mail:

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 81720108021); Medical Science and Technology Research Project of Henan Province (No. SBGJ202101002).
Received  2022-07-29
Accepted  2022-10-13
DOI: 10.12015/issn.1674-8034.2022.11.021
Cite this article as: Li Q, Yue XP, Bai Y, et al. Application value of multi-modal imaging technique in early diagnosis of Alzheimer's disease[J]. Chin J Magn Reson Imaging, 2022, 13(11): 110-114. DOI:10.12015/issn.1674-8034.2022.11.021.

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