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Opportunities and challenges of non-contrast-enhanced magnetic resonance imaging: Achievements and prospects over the past decade in China
WANG Feng  CAO Dairong 

Cite this article as: Wang F, Cao DR. Opportunities and challenges of non-contrast-enhanced magnetic resonance imaging: Achievements and prospects over the past decade in China[J]. Chin J Magn Reson Imaging, 2022, 13(10): 46-52, 60. DOI:10.12015/issn.1674-8034.2022.10.006.

[Abstract] Over the past decade, with the development of magnetic resonance software and hardware, non-contrast-enhanced magnetic resonance imaging sequences have also been continuously developed and refined. Due to the advantages of non-invasiveness, non-radiation, and no need to inject contrast agents, this technology has gained widespread attention and promotion. The combination with the MRI acceleration technology further shortens the scan time and relieves the suffering of intolerant patients. Non-contrast-enhanced magnetic resonance imaging has become a common method for evaluating vascular problems today. This paper reviews the basic principles, advantages and disadvantages, clinical applications and latest progress of non-contrast-enhanced magnetic resonance imaging sequences from the two entry points of bright blood technology and black blood technology.Based on the current shortcomings, the simultaneous reconstruction of multiple contrast images in a single scan and the combination of 3D black blood sequence with electrocardiogram gating and respiratory gating will be a major research direction in the future. Multi site and even whole body non-contrast-enhanced magnetic resonance angiography combined scanning will also become a trend.
[Keywords] non-contrast-enhanced magnetic resonance imaging;bright blood technique;black blood technique;magnetic resonance imaging

WANG Feng1   CAO Dairong1, 2, 3*  

1 Department of Radiology, the First Affiliated Hospital of Fujian Medical University, Key Clinical Specialty in Fujian Province, Fuzhou 350005, China

2 Fujian Key Laboratory of Precision Medicine for Cancer, Fuzhou 350005, China

3 Key Laboratory of Radiation Biology of Fujian Higher Education Institutions, Fuzhou 350005, China

Cao DR, E-mail:

Conflicts of interest   None.

Received  2022-09-01
Accepted  2022-10-14
DOI: 10.12015/issn.1674-8034.2022.10.006
Cite this article as: Wang F, Cao DR. Opportunities and challenges of non-contrast-enhanced magnetic resonance imaging: Achievements and prospects over the past decade in China[J]. Chin J Magn Reson Imaging, 2022, 13(10): 46-52, 60.DOI:10.12015/issn.1674-8034.2022.10.006

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