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Progress in MRI study of brain structure and functional alterations in patients with Crohn's disease
TANG Wuli  LI Kang 

Cite this article as: Tang WL, Li K. Progress in MRI study of brain structure and functional alterations in patients with Crohn's disease[J]. Chin J Magn Reson Imaging, 2022, 13(8): 154-157. DOI:10.12015/issn.1674-8034.2022.08.035.

[Abstract] Crohn's disease (CD) is a kind of recurrent inflammatory bowel disease which has unknown etiology. A growing number of researches suggest that the brain-gut axis plays a critical role in the development of this disease, and some patients present clinical symptoms such as anxiety, depression, and psychological disorders. However, long-term anxiety, depression or high psychological stress may lead to the recurrence of the disease. Therefore, the psycho-psychiatric status of the patients should be high valued in the treatment process. Currently, functional magnetic resonance imaging, which includes task state and resting state, has been widely used to study structural and functional aspects of the brain, and some progress has been made. This article reviews the progress of MRI research on structural and functional brain alterations in patients with CD, so as to provide a neuroimaging basis for further optimizing the treatment strategies of these patients.
[Keywords] Crohn's disease;functional magnetic resonance imaging;brain-gut axis;anxiety;depression

TANG Wuli1, 2   LI Kang2*  

1 Chongqing Medical University, Chongqing 400016, China

2 Department of Radiology, Chongqing General Hospital, Chongqing 401147, China

Li K, E-mail:

Conflicts of interest   None.

ACKNOWLEDGMENTS Chongqing Science and Technology Bureau of Science and Technology Innovation and Application Development Special (No. cstc2020jscx-sbqwX0015); Chongqing Science and Health Joint Project (No. 2019ZDXM008).
Received  2022-03-31
Accepted  2022-07-26
DOI: 10.12015/issn.1674-8034.2022.08.035
Cite this article as: Tang WL, Li K. Progress in MRI study of brain structure and functional alterations in patients with Crohn's disease[J]. Chin J Magn Reson Imaging, 2022, 13(8): 154-157. DOI:10.12015/issn.1674-8034.2022.08.035.

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