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A comparison of the Kaiser score and apparent diffusion coefficient mapping in the assessment of breast lesions
PAN Jialing  LI Xiaohong  CHEN Xinjie  DENG Lingda  DU Yongxing  CHEN Haixiong  YANG Shaomin  HU Qiugen  GUO Baoliang 

Cite this article as: Pan JL, Li XH, Chen XJ, et al. A comparison of the Kaiser score and apparent diffusion coefficient mapping in the assessment of breast lesions[J]. Chin J Magn Reson Imaging, 2022, 13(6): 108-111, 116. DOI:10.12015/issn.1674-8034.2022.06.021.

[Abstract] Objective To compare the diagnostic performance of Kaiser score with apparent diffusion coefficient (ADC) to distinguish benign from breast malignant lesions and to assess the potential of those approaches to avoid unnecessary biopsies.Materials and Methods This retrospective study enrolled 127 patients with 134 lesions (7 patients had 2 lesions) undergoing breast MRI from January 2019 to September 2021. KS+ score was calculated by combining ADC and Kaiser score. With pathological results as the gold standard, the area under the receiver operating characteristics curve (AUC) was calculated and compared between Kaiser score, ADC and KS+ score through Delong Test. Sensitivity and specificity were calculated and compared between them through McNemar Test.Results The AUC of Kaiser score (0.917) was significantly different from that of ADC (0.812) (P=0.0404), and the largest difference was found in non-mass lesions. There were statistically significant differences in specificity between Kaiser score (0.809) and ADC (0.426) (P=0.0215), but no difference in sensitivity between Kaiser score (0.954) and ADC (0.977) (P=0.6875). There were no differences between the AUC (0.917)、sensitivity (0.954) and specificity (0.809) of the Kaiser score and the AUC (0.914)、sensitivity (0.943) and specificity (0.830) of the KS+ score (P>0.05).Conclusions Kaiser score is superior to ADC in distinguishing benign from malignant breast lesions, especially in non-mass enhancement lesions. Kaiser score also performs better in avoiding unnecessary biopsies compared with ADC. The combination of the Kaiser score and ADC does not contribute to the diagnosis of breast cancer.
[Keywords] breast;magnetic resonance imaging;Kaiser score;apparent diffusion coefficient

PAN Jialing1   LI Xiaohong1   CHEN Xinjie1   DENG Lingda1   DU Yongxing1   CHEN Haixiong1   YANG Shaomin1, 2   HU Qiugen1   GUO Baoliang1*  

1 Department of Radiology, Shunde Hospital of Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan 528300 ,China

2 Department of Radiology, Shunde Hospital affiliated to Guangzhou Medical University (YueCong Hospital of Shunde, Foshan), Foshan 528300, China

Guo BL, E-mail:

Conflicts of interest   None.

Received  2022-01-30
Accepted  2022-05-23
DOI: 10.12015/issn.1674-8034.2022.06.021
Cite this article as: Pan JL, Li XH, Chen XJ, et al. A comparison of the Kaiser score and apparent diffusion coefficient mapping in the assessment of breast lesions[J]. Chin J Magn Reson Imaging, 2022, 13(6): 108-111, 116.DOI:10.12015/issn.1674-8034.2022.06.021

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