Share:
Share this content in WeChat
X
Reviews
Research progress of multimodal functional magnetic resonance imaging in high intensive focused ultrasound ablation of uterus myomas
JIANG Yu  HUANG Xiaohua  TANG Lingling  QIN Shize  ZHONG Shuting 

Cite this article as: Jiang Y, Huang XH, Tang LL, et al. Research progress of multimodal functional magnetic resonance imaging in high intensive focused ultrasound ablation of uterus myomas[J]. Chin J Magn Reson Imaging, 2022, 13(4): 162-165. DOI:10.12015/issn.1674-8034.2022.04.036.


[Abstract] Uterus myomas are the most common gynecological benign tumors in women of childbearing age. High intensity focused ultrasound (HIFU) is a non-invasive technology for the treatment of uterus myomas, which relies on the thermal and mechanical energy of ultrasound to ablate the target tissue under the guidance of monitoring images, resulting in tissue coagulation necrosis. functional magnetic resonance imaging plays an important role in evaluating the efficacy and safety of HIFU ablation of uterus myomas. It can provide noninvasive functional, perfusion and metabolic information for the prediction of preoperative efficacy, postoperative efficacy evaluation and observation of surrounding tissue changes. This article reviews the research progress of multimodal functional magnetic resonance imaging in HIFU ablation of uterus myomas.
[Keywords] magnetic resonance imaging;uterus myoma;high intensive focused ultrasound;efficacy assessment;dynamic contrast-enhanced magnetic resonance imaging;diffusion weighted imaging

JIANG Yu   HUANG Xiaohua*   TANG Lingling   QIN Shize   ZHONG Shuting  

Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

Huang XH, E-mail: 15082797553@163.com

Conflicts of interest   None.

Received  2021-12-22
Accepted  2022-04-07
DOI: 10.12015/issn.1674-8034.2022.04.036
Cite this article as: Jiang Y, Huang XH, Tang LL, et al. Research progress of multimodal functional magnetic resonance imaging in high intensive focused ultrasound ablation of uterus myomas[J]. Chin J Magn Reson Imaging, 2022, 13(4): 162-165.DOI:10.12015/issn.1674-8034.2022.04.036

[1]
Chinese Expert Consensus Group on Diagnosis and Treatment of Uterine Leiomyoma. Chinese expert consensus on the diagnosis and treatment of uterine fibroids[J]. Chin J Obstet Gynecol, 2017, 52(12): 793-800. DOI: 10.3760/cma.j.issn.0529-567x.2017.12.001.
[2]
Schlaff WD, Ackerman RT, Al-Hendy A, et al. Elagolix for heavy menstrual bleeding in women with uterine fibroids[J]. N Engl J Med, 2020, 382(4): 328-340. DOI: 10.1056/NEJMoa1904351.
[3]
Al Ansari AA, Al Hail FA, Abboud E. Malignant transformation of uterine leiomyoma[J]. Qatar Med J, 2012, 2012(2): 16. DOI: 10.5339/qmj.2012.2.16.
[4]
Jeng CJ, Ou KY, Long CY, et al. 500 cases of high-intensity focused ultrasound (HIFU) ablated uterine fibroids and adenomyosis[J]. Taiwan J Obstet Gynecol, 2020, 59(6): 865-871. DOI: 10.1016/j.tjog.2020.09.013.
[5]
Marinova M, Ghaei S, Recker F, et al. Efficacy of ultrasound-guided high-intensity focused ultrasound (USgHIFU) for uterine fibroids: an observational single-center study[J]. Int J Hyperthermia, 2021, 38(2): 30-38. DOI: 10.1080/02656736.2021.1939444.
[6]
Anneveldt KJ, van 't Oever HJ, Nijholt IM, et al. Systematic review of reproductive outcomes after High Intensity Focused Ultrasound treatment of uterine fibroids[J]. Eur J Radiol, 2021, 141: 109801. DOI: 10.1016/j.ejrad.2021.109801.
[7]
Krzyzanowski J, Wozniak S, Szkodziak P, et al. Minimally invasive treatment options for uterine fibroids-state-of-the art 2021[J]. Ginekol Pol, 2022. DOI: 10.5603/GP.a2021.0202.
[8]
Lynn JG, Zwemer RL, Chick AJ, et al. A new method for the generation and use of focused ultrasound in experimental biology[J]. J Gen Physiol, 1942, 26(2): 179-193. DOI: 10.1085/jgp.26.2.179.
[9]
Napoli A, Alfieri G, Andrani F, et al. Uterine myomas: focused ultrasound surgery[J]. Semin Ultrasound CT MR, 2021, 42(1): 25-36. DOI: 10.1053/j.sult.2020.08.001.
[10]
Zhou YF. High intensity focused ultrasound in clinical tumor ablation[J]. World J Clin Oncol, 2011, 2(1): 8-27. DOI: 10.5306/wjco.v2.i1.8.
[11]
Yang MJ, Yu RQ, Chen WZ, et al. A prediction of NPVR≥80% of ultrasound-guided high-intensity focused ultrasound ablation for uterine fibroids[J]. Front Surg, 2021, 8: 663128. DOI: 10.3389/fsurg.2021.663128.
[12]
Funaki K, Sawada K, Maeda F, et al. Subjective effect of magnetic resonance-guided focused ultrasound surgery for uterine fibroids[J]. J Obstet Gynaecol Res, 2007, 33(6): 834-839. DOI: 10.1111/j.1447-0756.2007.00665.x.
[13]
Gong CM, Lin ZJ, Lv FJ, et al. Magnetic resonance imaging parameters in predicting the ablative efficiency of high-intensity focused ultrasound for uterine fibroids[J]. Int J Hyperthermia, 2021, 38(1): 523-531. DOI: 10.1080/02656736.2021.1904152.
[14]
Verpalen IM, Anneveldt KJ, Vos PC, et al. Use of multiparametric MRI to characterize uterine fibroid tissue types[J]. MAGMA, 2020, 33(5): 689-700. DOI: 10.1007/s10334-020-00841-9.
[15]
Zhao WP, Chen JY, Chen WZ. Dynamic contrast-enhanced MRI serves as a predictor of HIFU treatment outcome for uterine fibroids with hyperintensity in T2-weighted images[J]. Exp Ther Med, 2016, 11(1): 328-334. DOI: 10.3892/etm.2015.2879.
[16]
Łoziński T, Ciebiera M, Łuczyńska E, et al. Magnetic Resonance-Guided High-Intensity Focused Ultrasound Ablation of Uterine Fibroids-Efficiency Assessment with the Use of Dynamic Contrast-Enhanced Magnetic Resonance Imaging and the Potential Role of the Administration of Uterotonic Drugs[J]. Diagnostics (Basel, Switzerland), 2021, 11(4): 715. DOI: 10.3390/diagnostics11040715.
[17]
Wei C, Fang X, Wang CB, et al. The predictive value of quantitative DCE metrics for immediate therapeutic response of high-intensity focused ultrasound ablation (HIFU) of symptomatic uterine fibroids[J]. Abdom Radiol (NY), 2018, 43(8): 2169-2175. DOI: 10.1007/s00261-017-1426-7.
[18]
Wang W, Zhang XD, Li Y, et al. The preliminary value of DCE-MRI quantitative parameters in high intensity focused ultrasound (HIFU) ablation's immediate effect for uterine fibroids[J]. Chin J Magn Reson Imaging, 2015, 6(8): 603-607. DOI: 10.3969/j.issn.1674-8034.2015.08.009.
[19]
Lozinski T, Filipowska J, Krol P, et al. Oxytocin administration in high-intensity focused ultrasound treatment of myomata[J]. Biomed Res Int, 2018, 2018: 7518026. DOI: 10.1155/2018/7518026.
[20]
Otonkoski S, Sainio T, Komar G, et al. Oxytocin selectively reduces blood flow in uterine fibroids without an effect on myometrial blood flow: a dynamic contrast enhanced MRI evaluation[J]. Int J Hyperthermia, 2020, 37(1): 1293-1300. DOI: 10.1080/02656736.2020.1846792.
[21]
Li CX, Jin C, Liang T, et al. Magnetic resonance-guided high-intensity focused ultrasound of uterine fibroids: whole-tumor quantitative perfusion for prediction of immediate ablation response[J]. Acta Radiol, 2020, 61(8): 1125-1133. DOI: 10.1177/0284185119891692.
[22]
Verpalen IM, Anneveldt KJ, Vos PC, et al. Use of multiparametric MRI to characterize uterine fibroid tissue types[J]. MAGMA, 2020, 33(5): 689-700. DOI: 10.1007/s10334-020-00841-9.
[23]
Sainio T, Saunavaara J, Komar G, et al. Feasibility of apparent diffusion coefficient in predicting the technical outcome of MR-guided high-intensity focused ultrasound treatment of uterine fibroids-a comparison with the Funaki classification[J]. Int J Hyperthermia, 2021, 38(1): 85-94. DOI: 10.1080/02656736.2021.1874545.
[24]
Zheng YN, Chen LP, Liu MQ, et al. Prediction of clinical outcome for high-intensity focused ultrasound ablation of uterine leiomyomas using multiparametric MRI radiomics-based machine leaning model[J]. Front Oncol, 2021, 11: 618604. DOI: 10.3389/fonc.2021.618604.
[25]
Liao DF, Xiao ZB, Lv FR, et al. Non-contrast enhanced MRI for assessment of uterine fibroids' early response to ultrasound-guided high-intensity focused ultrasound thermal ablation[J]. Eur J Radiol, 2020, 122: 108670. DOI: 10.1016/j.ejrad.2019.108670.
[26]
Liu J, Bi ZX, Liu J, et al. Intravoxel incoherent motion MRI in assessment of mid-term therapeutic effect of MR-guided high-intensity focused ultrasound for uterine fibroids[J]. Chin J Med Imaging Technol, 2021, 37(8): 1191-1195. DOI: 10.13929/j.issn.1003-3289.2021.08.017.
[27]
Wang MJ, Li CY, Chen MH, et al. Evaluation of the effects of 3.0 T MRI combined with diffusion weighted imaging on the adjacent tissues in the early postoperative period of high-intensity focused ultrasound in uterine leiomyoma[J]. J Hebei Med Univ, 2018, 39(1): 86-90, 96. DOI: 10.3969/j.issn.1007-3205.2018.01.019.
[28]
Andrews S, Yuan Q, Bailey A, et al. Multiparametric MRI characterization of funaki types of uterine fibroids considered for MR-guided high-intensity focused ultrasound (MR-HIFU) therapy[J]. Acad Radiol, 2019, 26(4): e9-e17. DOI: 10.1016/j.acra.2018.05.012.
[29]
Quan XH, Wang K. Value of intravoxel incoherent motion diffusion weighted imaging in evaluating efficacy of HIFU in the treatment of uterine leiomyoma[J]. Acta Agric Shanghai, 2021, 38(3): 379-381. DOI: 10.3969/j.issn.1671-7171.2021.03.017.
[30]
Thrippleton MJ, Bastin ME, Munro KI, et al. Ex vivo water diffusion tensor properties of the fibroid uterus at 7 T and their relation to tissue morphology[J]. J Magn Reson Imaging, 2011, 34(6): 1445-1451. DOI: 10.1002/jmri.22793.
[31]
Zhou FL, Lv FR, Lv FJ, et al. The predictive value of quantitative DTI fibre tractography metrics for ablation effect of high intensity focused ultrasound in treating uterine fibroids[J]. J Clin Radiol, 2020, 39(1): 206-211. DOI: 10.13437/j.cnki.jcr.2020.01.043.
[32]
Han Y, Sun CF, Wang X, et al. Clinical value of dti in evaluation of high intensity focused ultrasound in uterine fibroids[J]. J Pract Med, 2017, 33(15): 2486-2488.
[33]
Obrzut M, Obrzut B, Zmuda M, et al. Uterine leiomyomas: correlation between histologic composition and stiffness via magnetic resonance elastography-a Pilot Study[J]. Ginekol Pol, 2020, 91(7): 373-378. DOI: 10.5603/GP.a2020.0067.
[34]
Stewart EA, Taran FA, Chen J, et al. Magnetic resonance elastography of uterine leiomyomas: a feasibility study[J]. Fertil Steril, 2011, 95(1): 281-284. DOI: 10.1016/j.fertnstert.2010.06.004.
[35]
Ichikawa S, Motosugi U, Omori M, et al. MR-guided focused ultrasound for uterine fibroids: a preliminary study of relationship between the treatment outcomes and factors of MR images including elastography[J]. Magn Reson Med Sci, 2019, 18(1): 82-87. DOI: 10.2463/mrms.tn.2017-0103.
[36]
Jondal DE, Wang J, Chen J, et al. Uterine fibroids: correlations between MRI appearance and stiffness via magnetic resonance elastography[J]. Abdom Radiol (NY), 2018, 43(6): 1456-1463. DOI: 10.1007/s00261-017-1314-1.

PREV Research progress of deep learning and radiomics in glioma
NEXT Research progress of anterior cruciate ligament injury of knee using MRI: Based on deep learning
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn