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Comparative study of 3D-FLAIR sequence based on compressed sensing and the conventional 2D-FLAIR sequence in white matter lesion imaging
ZHANG Yueqing  DING Jinli  GONG Tao  CHEN Xuzhu  ZHENG Fenglian  ZHANG Yanbo  FAN Yilong  LIN Liangjie 

Cite this article as: Zhang YQ, Ding JL, Gong T, et al. Comparative study of 3D-FLAIR sequence based on compressed sensing and the conventional 2D-FLAIR sequence in white matter lesion imaging[J]. Chin J Magn Reson Imaging, 2022, 13(4): 100-102, 119. DOI:10.12015/issn.1674-8034.2022.04.018.

[Abstract] Objective To compare the imaging quality of 3D-FLAIR sequence based on compressed sensing (CS) with the conventional 2D-FLAIR sequence in detection of brain white matter lesions.Materials and Methods Forty patients with white matter lesions who underwent both CS 3D-FLAIR and 2D-FLAIR were analyzed. The signal-to-noise ratio (SNR) and contrast noise ratio (CNR) of the images were calculated. The overall image quality and number of the white matter lesions were evaluated by two experienced radiologists. Statistical analysis was performed by Wilcoxon assay.Results The acquisition time of 3D-FLAIR sequence by using CS technique could be shorted to be equal to that of 2D-FLAIR sequence. No significant differences were observed for the SNR and CNR between the CS 3D-FLAIR and 2D-FLAIR sequences (Z=-1.18, P=0.24; Z=-1.92, P=0.14). The overall image quality for CS 3D-FLAIR sequence were better than the 2D-FLAIR sequence (Z=-3.99, P<0.001), and more white matter lesions were detected from the CS 3D-FLAIR sequence than those from the 2D-FLAIR sequence (Z=-3.75, P=0.006). The pulsatile artifactsin the fourth-ventricle layer on the 2D-FLAIR images were suppressed on the CS 3D-FLAIR images.Conclusions In the case of the same acquisition time, the advantages of the CS 3D-FLAIR, including better overall image quality and suppressed pulsation artifacts, make it more attractive in the detection of white matter lesions than the 2D-FLAIR, which is recommended for clinical application.
[Keywords] magnetic resonance imaging;fluid-attenuated inversion recovery;compressed sensing;white matter lesions

ZHANG Yueqing1   DING Jinli1*   GONG Tao2   CHEN Xuzhu1   ZHENG Fenglian1   ZHANG Yanbo1   FAN Yilong1   LIN Liangjie3  

1 Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China

2 Department of Radiology, Yichun People's Hospital, Yichun 336099, China

3 Philips (China) Investment Co., LTD, Beijing 100102, China

Ding JL, E-mail:

Conflicts of interest   None.

Received  2021-11-30
Accepted  2022-04-01
DOI: 10.12015/issn.1674-8034.2022.04.018
Cite this article as: Zhang YQ, Ding JL, Gong T, et al. Comparative study of 3D-FLAIR sequence based on compressed sensing and the conventional 2D-FLAIR sequence in white matter lesion imaging[J]. Chin J Magn Reson Imaging, 2022, 13(4): 100-102, 119. DOI:10.12015/issn.1674-8034.2022.04.018.

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