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Clinical Article
The value of dynamic contrast enhanced-magnetic resonance imaging based on compressed sensing volumetric interpolated breath-hold examination in the differential diagnosis between benign and malignant thyroid nodules
CHEN Jiao  JIANG Liling  LIU Daihong  WU Jian  ZHANG Junbin  ZHANG Jiuquan 

Cite this article as: Chen J, Jiang LL, Liu DH, et al. The value of dynamic contrast enhanced-magnetic resonance imaging based on compressed sensing volumetric interpolated breath-hold examination in the differential diagnosis between benign and malignant thyroid nodules[J]. Chin J Magn Reson Imaging, 2022, 13(4): 38-42. DOI:10.12015/issn.1674-8034.2022.04.007.


[Abstract] Objective To explore the value of dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) based on compressed sensing volumetric interpolated breath-hold examination (CS-VIBE) in the differential diagnosis between benign and malignant thyroid nodules.Materials and Methods In this retrospective study, the patients with thyroids were enrolled from September 2020 to May 2021 in our hospital. A total of 84 nodules were included, including 43 malignant nodules and 41 benign nodules. All patients were examined by routine MRI and DCE-MRI before the operation. The DCE-MRI parameters including volume transfer constant (Ktrans), rate constant (Kep), extracellular space volume fraction (Ve) and initial area under curve (iAUC) were acquired. The difference of quantitative parameters between benign and malignant thyroid nodules was compared. The binary logistic regression analysis was used to build prediction model. The receiver operating characteristic (ROC) curces were performed to evaluate the diagnostic performance.Results The malignant group had a significantly higher Ktrans value (P<0.001), Kep value (P<0.001) and iAUC value (P=0.001) than the benign group. The Ve value was not significantly different between malignant and benign nodules (P=0.177). In the prediction model, the sensitivity and specificity were 83.33% and 73.81%, respectively.Conclusions The DCE-MRI with CS-VIBE had good diagnostic performance in the differential diagnosis between benign and malignant thyroid nodules.
[Keywords] dynamic contrast enhanced;magnetic resonance imaging;compressed sensing volumetric interpolated breath-hold examination;thyroid nodules;differential diagnosis

CHEN Jiao1   JIANG Liling1   LIU Daihong1   WU Jian2   ZHANG Junbin2   ZHANG Jiuquan1*  

1 Department of Radiology, Chongqing University Cancer Hospital, Chongqing 400030, China

2 Head and Neck Cancer Center, Chongqing University Cancer Hospital, Chongqing 400030, China

Zhang JQ, E-mail: zhangjq_radiol@foxmail.com

Conflicts of interest   None.

Received  2021-11-16
Accepted  2022-03-16
DOI: 10.12015/issn.1674-8034.2022.04.007
Cite this article as: Chen J, Jiang LL, Liu DH, et al. The value of dynamic contrast enhanced-magnetic resonance imaging based on compressed sensing volumetric interpolated breath-hold examination in the differential diagnosis between benign and malignant thyroid nodules[J]. Chin J Magn Reson Imaging, 2022, 13(4): 38-42.DOI:10.12015/issn.1674-8034.2022.04.007

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