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Clinical Article
Evaluation of the relationship between cervicocranial artery dissection and acute ischemic stroke based on high-resolution MRI
LI Yan  LU Yao  YANG Wenrui  YANG Li  YE Jing  ZHANG Hongying 

Cite this article as: Li Y, Lu Y, Yang WR, et al. Evaluation of the relationship between cervicocranial artery dissection and acute ischemic stroke based on high-resolution MRI[J]. Chin J Magn Reson Imaging, 2022, 13(4): 32-37. DOI:10.12015/issn.1674-8034.2022.04.006.


[Abstract] Objective To discuss the influence factors of acute ischemic stroke caused by cervicocranial artery dissection (CCAD) based on high-resolution magnetic resonance imaging (HR-MRI).Materials and Methods A total of 73 patients with clinically confirmed CCAD were included in the study. According to their diffusion weighted imaging (DWI) manifestations, they were divided into stroke and non-stroke groups. We collected the clinical and imaging data of all patients. The relationship between CCAD and acute ischemic stroke was analyzed by univariate and multivariate Logistic regression.Results A total of 73 patients with dissection and 85 dissection vessels were included in the study, 45 patients and 54 dissection vessels were included in stroke group, 28 patients and 31 dissection vessels were included in non-stroke group. The prevalence of hypertension in stroke group [34 (75.56%)] was higher than that in non-stroke group [11 (39.29%)], the difference was statistically significant (P=0.002). Multivariate Logistic regression analysis showed that there were significant differences in hypertension, mild stenosis, severe lumen stenosis, lumen occlusion, intimal flap and pseudoaneurysm between the two groups (both P<0.05). Hypertension, severe lumen stenosis, lumen occlusion and intimal flap were significantly correlated with acute ischemic stroke (OR=4.507, 5.457, 7.596, 3.745, both P<0.05). Mild stenosis and pseudoaneurysm were more common in non-stroke group.Conclusions Hypertension is the risk factor of acute ischemic stroke caused by CCAD. There are some differences in the imaging manifestations of CCAD patients with or without stroke, which has a certain reference value for the individual prediction of early ischemic stroke in CCAD.
[Keywords] acute ischemic stroke;cervicocranial artery dissection;high-resolution magnetic resonance imaging;intimal flap;pseudoaneurysm;hypertension

LI Yan1, 2   LU Yao2, 3   YANG Wenrui1, 2   YANG Li1, 2   YE Jing2   ZHANG Hongying2*  

1 Dalian Medical University, Dalian 116044, China

2 Department of Imaging, Subei People's Hospital, Yangzhou 225001, China

3 Yangzhou University, Yangzhou 225001, China

Zhang HY, E-mail: zhying11@aliyun.com

Conflicts of interest   None.

Received  2021-10-26
Accepted  2022-03-29
DOI: 10.12015/issn.1674-8034.2022.04.006
Cite this article as: Li Y, Lu Y, Yang WR, et al. Evaluation of the relationship between cervicocranial artery dissection and acute ischemic stroke based on high-resolution MRI[J]. Chin J Magn Reson Imaging, 2022, 13(4): 32-37.DOI:10.12015/issn.1674-8034.2022.04.006

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