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Clinical Articles
The value of FLAIR vascular hyperintensity-diffusion weighted imaging mismatch in assessing collateral circulation in acute ischemic stroke
QIU Yanhua  HUANG Lidong  CHEN Qiuyan  WENG Ye  SHI Liwei  WEI Dingtai 

Cite this article as: Qiu YH, Huang LD, CHEN QY, et al. The value of FLAIR vascular hyperintensity-diffusion weighted imaging mismatch in assessing collateral circulation in acute ischemic stroke[J]. Chin J Magn Reson Imaging, 2022, 13(3): 6-11, 65. DOI:10.12015/issn.1674-8034.2022.03.002.


[Abstract] Objective To evaluate the clinical value of fluid-attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH)-diffusion weighted imaging (DWI) mismatch in collateral circulation in patients with acute ischemic stroke (AIS).Materials and Methods We enrolled 37 patients with AIS. FVH, DWI lesion volume, FVH-DWI mismatch, arterial transit artifact (ATA), arterial spin labeling-cerebral blood flow (ASL-CBF) abnormal perfusion and clinical data including 90-day clinical outcome were collected to analyze the correlation between them.Results Compared to the no FVH-DWI mismatch group, patient with FVH-DWI mismatch had a higher FVH scores (4.57±1.87 vs. 1.13±2.24, P<0.001), a higher ATA scores (1.36±0.50 vs. 0.22±0.60, P<0.001), a higher proportion ASL perfusion abnormalities (P=0.001). FVH was highly associated with ASL-CBF abnormal perfusion (r=0.837, P<0.001), and in most cases, the range of FVH was close to the abnormal perfusion region of ASL-CBF. In the correlation analysis between ATA and FVH, FVH-DWI mismatch, we found that the correlation between ATA and FVH-DWI mismatch was better than that between ATA and FVH [(r=0.846, P<0.001) vs. (r=0.632, P<0.001)].Conclusions FVH-DWI mismatch was highly correlated with the ASL collateral circulation index ATA, which is helpful for clinical judgment of prognosis and guidance of treatment.
[Keywords] acute ischemic stroke;fluid-attenuated inversion recovery;diffusion weighted imaging;arterial transit artifact;arterial spin labeling

QIU Yanhua1, 2, 3   HUANG Lidong1, 2, 3   CHEN Qiuyan2, 3   WENG Ye1, 2, 3   SHI Liwei1, 2, 3   WEI Dingtai1, 2, 3*  

1 The Third Clinical Medical College, Fujian Medical University, Fuzhou 350000, China

2 Department of Radiology, Ningde Hospital Affiliated to Ningde Normal University, Ningde 352100, China

3 Functional and Molecular Imaging Laboratory for Cerebral Vascular Diseases, Ningde Hospital Affiliated to Ningde Normal University, Ningde 352100, China

Wei DT, E-mail: wdtai83@163.com

Conflicts of interest   None.

Received  2021-08-17
Accepted  2022-02-17
DOI: 10.12015/issn.1674-8034.2022.03.002
Cite this article as: Qiu YH, Huang LD, CHEN QY, et al. The value of FLAIR vascular hyperintensity-diffusion weighted imaging mismatch in assessing collateral circulation in acute ischemic stroke[J]. Chin J Magn Reson Imaging, 2022, 13(3): 6-11, 65.DOI:10.12015/issn.1674-8034.2022.03.002

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