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Technical Article
The effect of bandwidth on evaluation of T1, T2 relaxation times and proton density using synthetic MRI: A phantom study
ZHENG Zuofeng  WANG Zhenchang  YIN Hongxia  YANG Jiafei  ZHANG Dongpo  MA Jun 

Cite this article as: Zheng ZF, Wang ZC, Yin HX, et al. The effect of bandwidth on evaluation of T1, T2 relaxation times and proton density using synthetic MRI: A phantom study[J]. Chin J Magn Reson Imaging, 2022, 13(1): 98-102. DOI:10.12015/issn.1674-8034.2022.01.019.

[Abstract] Objective To evaluate the effect of bandwidth on quantification of T1, T2 relaxation times and proton density using multi-dynamic multi-echo sequence.Materials and Methods: Phantoms consisting of 3 kinds of materials with different T1, T2 and PD [gray matter (GM), white matter (WM), cerebrospinal fluid (CSF)] were included in the study. The phantoms were scanned 9 times using MDME sequence with 7 sets of scan parameters with different bandwidths (19.23 kHz—100.00 kHz). T1, T2, and PD maps were acquired and processed using MAGiC (magnetic resonance imaging compilation) post-processing software, and T1, T2, PD values were acquired. Intragroup coefficient of variation (CV) was performed to evaluate the reproducibility of measured values. Intergroup CV was used to evaluate the discrepancy of measured values across all the groups. The T1, T2 values between GM and WM were compared with paired-samples t test. The PD values between GM and WM were compared with Wilcoxon singled Rank test. Statistical analysis was performed using SPSS software (SPSS for Windows,, IBM).Results The highest intragroup CVs of T1, T2 and PD were 2.09%, 8.73%, 10.61%, respectively. The highest intergroup CVs of T1, T2 and PD values were 1.36%, 2.85%, 3.72%, respectively. Significant differences were revealed when comparing T1 and T2 values between GM and WM (P<0.01) and no significant differences were found when comparing PD values between GM and WM (P>0.05).Conclusions T1 and T2 measurements are not affected by bandwidth within range of 19.23 kHz—100.00 kHz. Repeatability of PD measurements is reduced when the bandwidth is below 50 kHz.
[Keywords] synthetic magnetic resonance imaging;T1 relaxation;T2 relaxation;proton density

ZHENG Zuofeng1, 2   WANG Zhenchang1*   YIN Hongxia1   YANG Jiafei2   ZHANG Dongpo2   MA Jun2  

1 Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

2 Department of Radiology, Beijing ChuiYangLiu Hospital, Beijing, 100022, China

Wang ZC, E-mail:

Conflicts of interest   None.

Received  2021-07-27
Accepted  2021-11-09
DOI: 10.12015/issn.1674-8034.2022.01.019
Cite this article as: Zheng ZF, Wang ZC, Yin HX, et al. The effect of bandwidth on evaluation of T1, T2 relaxation times and proton density using synthetic MRI: A phantom study[J]. Chin J Magn Reson Imaging, 2022, 13(1): 98-102.DOI:10.12015/issn.1674-8034.2022.01.019

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