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Clinical Article
Preliminary study of CMR tissue feature tracking technology on left ventricular function in patients with hypertrophic cardiomyopathy with ejection fraction preservation
LIU Yuhao  LI Wei  OUYANG Lina  YANG Qin  WANG Yifan  SUN Xiao  ZHU Li 

Cite this article as: Liu YH, Li W, Ouyang LN, et al. Preliminary study of CMR tissue feature tracking technology on left ventricular function in patients with hypertrophic cardiomyopathy with ejection fraction preservation[J]. Chin J Magn Reson Imaging, 2022, 13(1): 31-36. DOI:10.12015/issn.1674-8034.2022.01.007.

[Abstract] Objective To explore the value of CMR tissue feature tracking technology for left ventricular strain in patients with hypertrophic cardiomyopathy (HCMpEF) with ejection fraction preserved.Materials and Methods: Seventy HCMpEF patients and 42 normal subjects (control group) were scanned with 3.0 T CMR steady-state free precession sequence, and the images were imported into CVI42 post-processing software to measure the basic function parameters of the left heart and the overall 3D strain parameters of the left ventricle. Including: radial, circumferential and longitudinal peak strain (PS), peak systolic strain rate (PSSR), peak diastolic strain rate (PDSR). The SPSS 26.0 software was used for statistical analysis of the two groups of parameters.Results The peak strain in all directions of the HCMpEF group was lower than that of the control group [radial: 26.00 (14.63) vs. 32.39 (10.55), circumferential: (-17.30±4.55) vs. (-19.67±3.73), longitudinal: (-8.14±3.25) vs. (-10.74±3.26), HCMpEF group vs. control group, unit: %], the difference was statistically significant (P<0.005); the PSSR and PDSR in each direction of HCMpEF group both are lower than the control group [PSSR radial: 1.55 (0.94) vs. 1.85 (0.61), circumferential: -0.99 (0.39) vs. -1.13 (0.29), longitudinal: -0.49 (0.38) vs. -0.67 (0.28), unit: s-1, P<0.05; PDSR radial: -1.37 (-0.86) vs. -2.17 (1.35), circumferential: 0.87 (2.44) vs. 1.16 (0.53), longitudinal: 0.46 (0.24) vs. 0.68 (0.33), unit: s-1], the difference was statistically significant (P<0.001).Conclusion Although the ejection fraction is preserved in HCMpEF patients, the systolic and diastolic functions have been impaired. The CMR-FT quantitative analysis technology can provide a new basis for evaluating cardiac function.
[Keywords] cardiovascular magnetic resonance;tissue feature tracking;heart function;strain;hypertrophic cardiomyopathy;ejection fraction

LIU Yuhao1   LI Wei1   OUYANG Lina1   YANG Qin2   WANG Yifan3   SUN Xiao3   ZHU Li3*  

1 Ningxia Medical University, Yinchuan 750000, China

2 Department of Radiology, Gansu Provincial People's Hospital, Lanzhou 730000, China

3 Department of Radiology, General Hospital of Ningxia Medical University,Yinchuan 750000, China

Zhu L, E-mail:

Conflicts of interest   None.

Received  2021-06-16
Accepted  2021-11-10
DOI: 10.12015/issn.1674-8034.2022.01.007
Cite this article as: Liu YH, Li W, Ouyang LN, et al. Preliminary study of CMR tissue feature tracking technology on left ventricular function in patients with hypertrophic cardiomyopathy with ejection fraction preservation[J]. Chin J Magn Reson Imaging, 2022, 13(1): 31-36.DOI:10.12015/issn.1674-8034.2022.01.007

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