Share:
Share this content in WeChat
X
Clinical Article
Dynamic contrast-enhanced MR imaging in differentiating postobstructive pneumonitis and atelectasis from central lung carcinoma
DANG Baohua  ZHAO Xin  ZHANG Xiaoan 

Cite this article as: Dang BH, Zhao X, Zhang XA. Dynamic contrast-enhanced MR imaging in differentiating postobstructive pneumonitis and atelectasis from central lung carcinoma. Chin J Magn Reson Imaging, 2019, 10(3): 195-200. DOI:10.12015/issn.1674-8034.2019.03.007.


[Abstract] Objective: To retrospectively evaluate dynamic contrast-enhanced MR imaging (DCE-MRI) for differentiating postobstructive pneumonitis and atelectasis from centrally located lung carcinomas, and to compare it with common MRI sequences and CT.Materials and Methods: Forty-four consecutive patients with central lung carcinoma proved pathologically between March 2017 to January 2018 were analyzed. All the patients underwent 3.0 T DCE-MRI, common MRI sequences and CT before treatment. MRI scan sequences were as followed, T1WI, T2WI, DWI and DCE-MRI. The detectability of different examines and sequences were statistically compared using χ2 test. The differences of signal intensity on DWI and ADC value between lung carcinomas and postobstructive pneumonitis and atelectasis were statistically compared using t test.Results: The detectability of CT, T1WI、T2WI、T2WI+DWI、DCE-MRI、T2WI+DWI+DCE-MRI was statistically different (χ2=74.756, P=0.000). The detectability of DCE-MRI was the same as T2WI combined DWI (75.0%, 33/44), and higher than T1WI (13.6%, 6/44), T2WI (50.0%, 22/44) or CT alone (40.9%, 18/44), and the differences were statistically significant (χ2=33.570, 5.867, 10.493, respectively, P<0.05). However, DCE-MRI can show the boundaryline clearer than T2WI combined DWI. The detectability can be the highest when DCE-MRI combined with T2WI and DWI (93.2%, 41/44). The mean signal intensity of lung carcinomas was higher than that of postobstructive pneumonitis and atelectasis on DWI images (P <0.05). The mean ADC value of lung carcinomas was significantly lower than that of postobstructive pneumonitis and atelectasis (P<0.05).Conclusions: DCE-MRI may be more useful than T1WI, T2WI and CT in differentiating postobstructive pneumonitis and atelectasis from central lung carcinoma, and it has more advantages for differential diagnosis when combined with T2WI and DWI.
[Keywords] lung neoplasms;pulmonary atelectasis;pneumonia;magnetic resonance imaging;tomography, x-ray computed

DANG Baohua* Department of Radiology, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

ZHAO Xin Department of Radiology, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

ZHANG Xiaoan Department of Radiology, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

*Correspondence to: Dang BH, E-mail: 382400313@qq.com

Conflicts of interest   None.

Received  2018-10-23
Accepted  2019-01-20
DOI: 10.12015/issn.1674-8034.2019.03.007
Cite this article as: Dang BH, Zhao X, Zhang XA. Dynamic contrast-enhanced MR imaging in differentiating postobstructive pneumonitis and atelectasis from central lung carcinoma. Chin J Magn Reson Imaging, 2019, 10(3): 195-200. DOI:10.12015/issn.1674-8034.2019.03.007.

[1]
Zhang X, Fu Z, Gong G, et al. Implementation of diffusion-weighted magnetic resonance imaging in target delineation of central lung cancer accompanied with atelectasis in precision radiotherapy. Oncol Lett, 2017, 14(3): 2677-2682.
[2]
Laurent F, Montaudon M, Corneloup O. CT and MRI of Lung Cancer. Respiration, 2006, 73(2): 133-142.
[3]
Yang RM, Li L, Wei XH, et al. Differentiation of central lung cancer from atelectasis: comparison of diffusion-weighted MRI with PET/CT. PLoS One, 2013, 8(4): e60279.
[4]
卢景海,任仲金.增强CT与MR压脂联合DWI对老年肺癌与肺不张组织的鉴别诊断价值.中国老年保健医学, 2015, 13(6): 98-99.
[5]
Baysal T, Mutlu DY, Yologlu S. Diffusion-weighted magnetic resonance imaging in differentiation of postobstructive consolidation from central lung carcinoma. Magn Reson Imaging, 2009, 27(10): 1447-1454.
[6]
盛美红,汤卫霞,陆益花,等. MRI动态增强扫描早期强化比值联合周围血管管径鉴别诊断乳腺良恶性病变的价值.中华放射学杂志, 2016, 50(5): 324-328.
[7]
Barentsz JO, Richenberg J, Clements R, et al. ESUR prostate MR guidelines 2012. Eur Radiol, 2012, 22(4): 746-757.
[8]
曲金荣,刘翠翠,张宏凯,等. CT和磁共振成像在肝细胞癌射频治疗后射频边缘评价中的作用.中国医学科学院学报, 2012, 34(5): 480-485.
[9]
聂凯.磁共振DWI在肺癌的诊断及分期中的应用进展.实用放射学杂志, 2018, 34(6): 955-958.
[10]
Ciliberto M, Kishida Y, Seki S, et al. Update of MR imaging for evaluation of lung cancer. Radiol Clin North Am, 2018, 56(3): 437-469.
[11]
解礼冰,田兴仓,马丽,等. DCE-MRI诊断肺癌和肺部不同类型良性肿块的价值.磁共振成像, 2018, 9(3): 192-196.
[12]
齐丽萍,张晓鹏,唐磊,等.扩散加权成像用于中央型肺癌与肺不张鉴别的初步研究.中国医学影像技术, 2007, 23(10): 1486-1490.
[13]
康进,牛朝霞,杨易. 3.0 T磁共振成像对中央型肺部占位性病变的诊断价值.中国CT和MRI杂志, 2016, 14(8): 62-65.
[14]
Inan N, Arslan A, Donmez M, et al. Diagnostic accuracy of dynamic contrast enhanced magnetic resonance imaging in characterizing lung masses. Iran J Radiol, 2016, 13(2): e23026.
[15]
Kono R, Fujimoto K, Terasaki H, et al. Dynamic MRI of solitary pulmonary nodules: comparison of enhancement patterns of malignant and benign small peripheral lung lesions. AJR Am J Roentgenol, 2007, 188(1): 26-36.

PREV Value of BOLD-MRI for the evaluation of short-term chemoradiotherapy efficacy in nasopharyngeal carcinoma
NEXT Application of 3.0 T whole body diffusion-weighted imaging for the evaluation of tumor response to induction chemotherapy in patients with multiple myeloma
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn